Antibiotic-resistant bacteria have become an alarming problem in hospitals. Hospital-based bacterial infections, in fact, now kill more people than diabetes. Worse, such infections are starting to appear outside of hospitals.
This makes it urgent to develop new antibiotics quickly. Most drug companies, though, aren’t interested, seeing the potential profits as limited. Today’s most profitable medications are those taken chronically, while antibiotics are short-term fixes that, moreover, are usually priced very modestly.
This leaves smaller companies leading the way—in particular, Cubist (CBST). Its major drug Cubicin treats skin, blood, and heart infections wholly or partly resistant to other antibiotics.
Cubicin sales, accounting for 80 percent of the company’s profits, have soared about sevenfold over the past six years, and we expect a few more years of rapid growth. But it’s still just one product with a limited life span. It was slated to face generic competition in 2020; to help shield its sales, Cubist entered into a profit-sharing agreement with generics leader Teva that will start in 2017 in exchange for a longer period of partial exclusivity.